ICD-10-PCS 2027 procedure code
X053X4BDestruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11
Short description: Destruc Brain w Focused Ultrasound, Extern, New Tech 11
Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data
About X053X4B
X053X4B is the ICD-10-PCS code for a destruction procedure on the brain using an external approach with focused ultrasound therapy (qualifier: new technology group 11). In ICD-10-PCS, destruction means physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent.
It is an operating-room procedure in the MS-DRG logic for DRG 025 (Craniotomy and Endovascular Intracranial Procedures with MCC), DRG 026 (Craniotomy and Endovascular Intracranial Procedures with CC), DRG 027 (Craniotomy and Endovascular Intracranial Procedures without CC/MCC), DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC) and DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC), under the surgical categories “Craniotomy and endovascular intracranial procedures”, “Lymphoma and Leukemia with Major O.R. Procedures”, “Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures” and 2 more.
It was added in FY2026, effective October 1, 2025.
What each character means
- 1. Section
- XNew Technology
- 2. Body System
- 0Nervous System
- 3. Operation
- 5Destruction
Physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent
None of the body part is physically taken out
Includes: Fulguration of rectal polyp, cautery of skin lesion
- 4. Body Part
- 3Brain
- 5. Approach
- XExternal
Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane
- 6. Device / Substance / Technology
- 4Focused Ultrasound Therapy
- 7. Qualifier
- BNew Technology Group 11
MS-DRG v44.0 grouping
All DRGs →Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.
MDC 01 · Diseases and Disorders of the Nervous System · Craniotomy and endovascular intracranial procedures
MDC 17 · Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms · Lymphoma and Leukemia with Major O.R. Procedures
MDC 17 · Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms · Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures
- 826Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCCRW 4.7581
- 827Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CCRW 2.3896
- 828Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures without CC/MCCRW 1.6955
MDC 21 · Injuries, Poisonings and Toxic Effects of Drugs · Other O.R. Procedures for Injuries
MDC 24 · Multiple Significant Trauma · Craniotomy for Multiple Significant Trauma
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2026 (effective 10/1/2025): Added
- No changes since FY2026.
Common questions about X053X4B
Is X053X4B a valid ICD-10-PCS code for 2027?
- Yes. X053X4B is valid for inpatient procedures from October 1, 2026 through September 30, 2027.
Is X053X4B an O.R. procedure?
- Yes. X053X4B is an O.R. procedure in MS-DRG v44.0.
What DRG does X053X4B group to?
- Depending on the principal diagnosis, X053X4B can group to MS-DRG 025, MS-DRG 026, MS-DRG 027, MS-DRG 820, MS-DRG 821 and MS-DRG 822.