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MS-DRG v44.0 · MDC 17: Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms

821 — Lymphoma and Leukemia with Major O.R. Procedures with CC

Source: CMS MS-DRG v44.0 and FY2027 IPPS final rule. Page updated September 29, 2026.
Relative weight
2.2023
Geometric mean LOS
3.1 days
Arithmetic mean LOS
4.9 days
Type
Surgical

About MS-DRG 821

MS-DRG 821, Lymphoma and Leukemia with Major O.R. Procedures with CC, is a surgical DRG in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms) under MS-DRG version 44.0, which applies to inpatient discharges from October 1, 2026 through September 30, 2027.

Its FY2027 relative weight is 2.2023, so Medicare's base payment for this DRG is about 2.20 times the average inpatient case, before hospital-specific adjustments. The geometric mean length of stay is 3.1 days and the arithmetic mean is 4.9 days.

It belongs to a 3-level severity family: DRG 820 (with MCC, weight 6.2481), DRG 821 (with CC, weight 2.2023) and DRG 822 (without CC/MCC, weight 1.1272). The highest-severity level carries 5.5 times the weight of the lowest, which is why documenting CC and MCC conditions matters.

552 ICD-10-CM diagnosis codes are part of this DRG's grouping logic; they are listed below.

ICD-10-CM codes that group to DRG 821 (552)

Chapter 2: Neoplasms

Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Common questions about DRG 821

What is the relative weight of DRG 821?

2.2023 for FY2027 (MS-DRG v44.0), from the IPPS final rule Table 5.

What is the average length of stay for DRG 821?

The geometric mean length of stay is 3.1 days; the arithmetic mean is 4.9 days.

Is DRG 821 medical or surgical?

DRG 821 is a surgical DRG.