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ICD-10-PCS 2027 procedure code

0F543Z3Destruction of Gallbladder using Laser Interstitial Thermal Therapy, Percutaneous Approach

✓ Valid for 2027O.R. procedure

Short description: Destruction of Gallbladder using LITT, Perc Approach

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 0F543Z3

0F543Z3 is the ICD-10-PCS code for a destruction procedure on the gallbladder using a percutaneous approach (qualifier: laser interstitial thermal therapy). In ICD-10-PCS, destruction means physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent.

For a different body part, codes include 0F503Z3 (liver), 0F513Z3 (liver, right lobe), 0F523Z3 (liver, left lobe), 0F553Z3 (right hepatic duct), 0F563Z3 (left hepatic duct), 0F573Z3 (hepatic duct, common) and 6 more.

The same procedure with a different approach is coded 0F540Z3 (open) and 0F544Z3 (percutaneous endoscopic).

It is an operating-room procedure in the MS-DRG logic for DRG 411 (Cholecystectomy with C.D.E. with MCC), DRG 412 (Cholecystectomy with C.D.E. with CC), DRG 413 (Cholecystectomy with C.D.E. without CC/MCC), DRG 414 (Cholecystectomy Except by Laparoscope without C.D.E. with MCC), DRG 415 (Cholecystectomy Except by Laparoscope without C.D.E. with CC) and DRG 416 (Cholecystectomy Except by Laparoscope without C.D.E. without CC/MCC), under the surgical categories “Cholecystectomy except by laparoscope”, “Lymphoma and Leukemia with Major O.R. Procedures”, “Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures” and 2 more.

It was added in FY2023, effective October 1, 2022.

What each character means

1. Section
0Medical and Surgical
2. Body System
FHepatobiliary System and Pancreas
3. Operation
5Destruction

Physical eradication of all or a portion of a body part by the direct use of energy, force, or a destructive agent

None of the body part is physically taken out

Includes: Fulguration of rectal polyp, cautery of skin lesion

4. Body Part
4Gallbladder
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device
ZNo Device
7. Qualifier
3Laser Interstitial Thermal Therapy

Other versions of this procedure

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about 0F543Z3

Is 0F543Z3 a valid ICD-10-PCS code for 2027?

Yes. 0F543Z3 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is 0F543Z3 an O.R. procedure?

Yes. 0F543Z3 is an O.R. procedure in MS-DRG v44.0.

What DRG does 0F543Z3 group to?

Depending on the principal diagnosis, 0F543Z3 can group to MS-DRG 411, MS-DRG 412, MS-DRG 413, MS-DRG 414, MS-DRG 415 and MS-DRG 416.