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ICD-10-CM 2027 diagnosis code

T88.0XXAInfection following immunization, initial encounter

✓ Billable / specificRequires 7th characterCC — complication/comorbidity

T88.0XXA is a valid, billable ICD-10-CM code for infection following immunization, initial encounter. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T88.0XXA

T88.0XXA is the ICD-10-CM diagnosis code for infection following immunization, initial encounter. It belongs to category T88 (other complications of surgical and medical care, not elsewhere classified), block T80-T88 (complications of surgical and medical care, not elsewhere classified) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

The 7th character "A" means initial encounter: use it while the patient is receiving active treatment for the condition.

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), DRG 856 (Postoperative or Post-Traumatic Infections with O.R. Procedures with MCC, relative weight 4.4826), DRG 857 (Postoperative or Post-Traumatic Infections with O.R. Procedures with CC, relative weight 2.1678), DRG 858 (Postoperative or Post-Traumatic Infections with O.R. Procedures without CC/MCC, relative weight 1.4036), DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC, relative weight 2.1859) and 2 more, in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period) and MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 999.39 (infection following other infusion, injection, transfusion, or vaccination).

7th character

Ainitial encounter

CC/MCC status for this injury by encounter: CC for A; Neither CC nor MCC for D, S.

Other encounter types for T88.0:

Notes that apply from higher levels

Instructions written at a parent level also apply to T88.0XXA.

› From T88 Other complications of surgical and medical care, not elsewhere classified
Excludes2
  • complication following infusion, transfusion and therapeutic injection (T80.-)
  • complication following procedure NEC (T81.-)
  • complications of anesthesia in labor and delivery (O74.-)
  • complications of anesthesia in pregnancy (O29.-)
  • complications of anesthesia in puerperium (O89.-)
  • complications of devices, implants and grafts (T82-T85)
  • complications of obstetric surgery and procedure (O75.4)
  • dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
  • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4)
  • specified complications classified elsewhere

Broader instructions also apply from T80-T88 Complications of surgical and medical care, not elsewhere classified and Chapter 19: Injury, poisoning and certain other consequences of external causes.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 999.39Infection following other infusion, injection, transfusion, or vaccinationapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T88.0XXA

Is T88.0XXA billable?

Yes. T88.0XXA is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

What does the "A" at the end of T88.0XXA mean?

It is the 7th character for initial encounter. Per the official guidelines, use it while the patient is receiving active treatment for the condition.

Can T88.0XXA be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict T88.0XXA as a principal diagnosis.

Is T88.0XXA a CC or MCC?

T88.0XXA is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does T88.0XXA group to?

T88.0XXA is used in the MS-DRG v44.0 logic for MS-DRG 791 (Prematurity with Major Problems), MS-DRG 793 (Full Term Neonate with Major Problems), MS-DRG 856 (Postoperative or Post-Traumatic Infections with O.R. Procedures with MCC), MS-DRG 857 (Postoperative or Post-Traumatic Infections with O.R. Procedures with CC), MS-DRG 858 (Postoperative or Post-Traumatic Infections with O.R. Procedures without CC/MCC), MS-DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC) and 2 more. Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for T88.0XXA?

The CMS General Equivalence Mappings map T88.0XXA to ICD-9-CM 999.39.