ICD-10-CM 2027 diagnosis code
T50.916AUnderdosing of multiple unspecified drugs, medicaments and biological substances, initial encounter
T50.916A is a valid, billable ICD-10-CM code for underdosing of multiple unspecified drugs, medicaments and biological substances, initial encounter. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Undrdose of multiple unspecified drug/meds/biol subst, init
Code last changed in FY2020 (effective October 1, 2019). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T50.916A
T50.916A is the ICD-10-CM diagnosis code for underdosing of multiple unspecified drugs, medicaments and biological substances, initial encounter. It belongs to category T50 (poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
The 7th character "A" means initial encounter: use it while the patient is receiving active treatment for the condition.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
It was added in FY2020, effective October 1, 2019.
7th character
Ainitial encounter
Other encounter types for T50.916:
Notes that apply from higher levels
Instructions written at a parent level also apply to T50.916A.
› From T50.91 Poisoning by, adverse effect of and underdosing of multiple unspecified drugs, medicaments and biological substances
- any specific drugs, medicaments and biological substances
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2020 (effective 10/1/2019): Added
- No changes since FY2020.
Common questions about T50.916A
Is T50.916A billable?
- Yes. T50.916A is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
What does the "A" at the end of T50.916A mean?
- It is the 7th character for initial encounter. Per the official guidelines, use it while the patient is receiving active treatment for the condition.
Can T50.916A be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is T50.916A a CC or MCC?
- No. T50.916A is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does T50.916A group to?
- T50.916A is used in the MS-DRG v44.0 logic for MS-DRG 951 (Other Factors Influencing Health Status). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.