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ICD-10-CM 2027 diagnosis code

T45.8X1Poisoning by other primarily systemic and hematological agents, accidental (unintentional)

Not billable — use a more specific codeRequires 7th character

T45.8X1 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.Short description: Poisn by oth primarily systemic and hematolog agents, acc

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T45.8X1

T45.8X1 is the ICD-10-CM diagnosis code for poisoning by other primarily systemic and hematological agents, accidental (unintentional). It belongs to category T45 (poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T45.8X, choose T45.8X1 (Poisoning by other primarily systemic and hematological agents, accidental (unintentional)) only when documentation doesn't support a more specific option: poisoning by other primarily systemic and hematological agents, intentional self-harm (T45.8X2), poisoning by other primarily systemic and hematological agents, assault (T45.8X3), poisoning by other primarily systemic and hematological agents, undetermined (T45.8X4), adverse effect of other primarily systemic and hematological agents (T45.8X5) and underdosing of other primarily systemic and hematological agents (T45.8X6).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

7th character

The appropriate 7th character is to be added to each code from category T45

Coding notes

Applicable toConditions and synonyms classified to this code
  • Poisoning by other primarily systemic and hematological agents NOS

Notes that apply from higher levels

Instructions written at a parent level also apply to T45.8X1.

› From T45.8 Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents
Excludes2
  • poisoning by, adverse effect of and underdosing of immunoglobulin (T50.Z1)
  • poisoning by, adverse effect of and underdosing of iron (T45.4)
  • transfusion reactions (T80.-)

Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.

Table of Drugs & Neoplasms entries

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T45.8X1

Is T45.8X1 billable?

No. T45.8X1 is a header code. Report one of its more specific subcodes instead.