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ICD-10-PCS 2027 procedure code

XW0431BIntroduction of Anitocabtagene Autoleucel Immunotherapy into Central Vein, Percutaneous Approach, New Technology Group 11

✓ Valid for 2027New for 2027Non-O.R. procedure

Short description: Introduce anito-cel in Central Vein, Perc, New Tech 11

Code last changed in FY2027 (effective October 1, 2026). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About XW0431B

XW0431B is the ICD-10-PCS code for a introduction procedure on the central vein using a percutaneous approach with anitocabtagene autoleucel immunotherapy (qualifier: new technology group 11). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

For a different body part, codes include XW0331B (peripheral vein).

With a different device, use XW0430B (alpha1-proteinase inhibitor), XW043FB (other new technology therapeutic substance), XW043PB (gentamicin-eluting bone void filler), XW043QB (iloprost), XW043RB (letetresgene autoleucel) and XW043WB (AGN1 bone void filler).

It is a non-O.R. procedure that is part of the MS-DRG logic for DRG 018 (Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies), under the surgical category “Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies”.

It was added in FY2027, effective October 1, 2026.

What each character means

1. Section
XNew Technology
2. Body System
WAnatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body Part
4Central Vein
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Device / Substance / Technology
1Anitocabtagene Autoleucel Immunotherapy

Includes: anito-cel

7. Qualifier
BNew Technology Group 11

Other versions of this procedure

Different body part

MS-DRG v44.0 grouping

All DRGs →

Surgical MS-DRGs this procedure can group to, depending on the principal diagnosis's MDC.

MDC PRE · Pre-MDC · Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2027 (effective 10/1/2026): Added

Common questions about XW0431B

Is XW0431B a valid ICD-10-PCS code for 2027?

Yes. XW0431B is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

Is XW0431B an O.R. procedure?

No. XW0431B is designated non-O.R. in MS-DRG v44.0.

What DRG does XW0431B group to?

Depending on the principal diagnosis, XW0431B can group to MS-DRG 018.