ICD-10-PCS 2027 procedure code
3E0R305Introduction of Other Antineoplastic into Spinal Canal, Percutaneous Approach
Short description: Introduce Oth Antineoplastic in Spinal Canal, Perc
Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data
About 3E0R305
3E0R305 is the ICD-10-PCS code for a introduction procedure on the spinal canal using a percutaneous approach with antineoplastic (qualifier: other antineoplastic). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.
In plain terms, this corresponds to implantation of chemotherapeutic agent and injection or infusion of cancer chemotherapeutic substance, the ICD-9-CM procedure titles it maps to (00.10 and 99.25).
For a different body part, codes include 3E01305 (subcutaneous tissue), 3E02305 (muscle), 3E03305 (peripheral vein), 3E04305 (central vein), 3E05305 (peripheral artery), 3E06305 (central artery) and 21 more.
It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.
It has been valid since ICD-10-PCS took effect on October 1, 2015.
What each character means
- 1. Section
- 3Administration
- 2. Body System
- EPhysiological Systems and Anatomical Regions
- 3. Operation
- 0Introduction
Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products
- 4. Body System / Region
- RSpinal Canal
- 5. Approach
- 3Percutaneous
Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure
- 6. Substance
- 0Antineoplastic
Includes: Amivantamab Monoclonal Antibody; Lurbinectedin; RYBREVANT (tm) (Amivantamab Monoclonal Antibody); ZEPZELCA(tm) (Lurbinectedin)
- 7. Qualifier
- 5Other Antineoplastic
Other versions of this procedure
Different body system / region
ICD-9-CM equivalent
Converter →- 00.10Implantation of chemotherapeutic agentapproximate
- 99.25Injection or infusion of cancer chemotherapeutic substanceapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about 3E0R305
Is 3E0R305 a valid ICD-10-PCS code for 2027?
- Yes. 3E0R305 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.
What is the ICD-9 procedure code for 3E0R305?
- The CMS GEMs map 3E0R305 to ICD-9-CM 00.10 (Implantation of chemotherapeutic agent) and 99.25 (Injection or infusion of cancer chemotherapeutic substance).