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ICD-10-PCS 2027 procedure code

3E0Q029Introduction of Other Anti-infective into Cranial Cavity and Brain, Open Approach

✓ Valid for 2027

Short description: Introduce Oth Anti-infect in Cran Cav/Brain, Open

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0Q029

3E0Q029 is the ICD-10-PCS code for a introduction procedure on the cranial cavity and brain using an open approach with anti-infective (qualifier: other anti-infective). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection of antibiotic, the ICD-9-CM procedure title it maps to (99.21).

For a different body part, codes include 3E03029 (peripheral vein), 3E04029 (central vein), 3E05029 (peripheral artery), 3E06029 (central artery) and 3E0U029 (joints).

The same procedure with a different approach is coded 3E0Q329 (percutaneous).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2017, effective October 1, 2016.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
QCranial Cavity and Brain
5. Approach
0Open

Cutting through the skin or mucous membrane and any other body layers necessary to expose the site of the procedure

6. Substance
2Anti-infective
7. Qualifier
9Other Anti-infective

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 99.21Injection of antibioticapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • No changes since FY2017.

Common questions about 3E0Q029

Is 3E0Q029 a valid ICD-10-PCS code for 2027?

Yes. 3E0Q029 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0Q029?

The CMS GEMs map 3E0Q029 to ICD-9-CM 99.21 (Injection of antibiotic).