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ICD-10-PCS 2027 procedure code

3E0Q004Introduction of Liquid Brachytherapy Radioisotope into Cranial Cavity and Brain, Open Approach

✓ Valid for 2027

Short description: Introduce Liquid Brachy in Cran Cav/Brain, Open

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0Q004

3E0Q004 is the ICD-10-PCS code for a introduction procedure on the cranial cavity and brain using an open approach with antineoplastic (qualifier: liquid brachytherapy radioisotope). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to infusion of liquid brachytherapy radioisotope, the ICD-9-CM procedure title it maps to (92.20).

The same procedure with a different approach is coded 3E0Q304 (percutaneous) and 3E0Q704 (via natural or artificial opening).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It was added in FY2017, effective October 1, 2016.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
QCranial Cavity and Brain
5. Approach
0Open

Cutting through the skin or mucous membrane and any other body layers necessary to expose the site of the procedure

6. Substance
0Antineoplastic

Includes: Amivantamab Monoclonal Antibody; Lurbinectedin; RYBREVANT (tm) (Amivantamab Monoclonal Antibody); ZEPZELCA(tm) (Lurbinectedin)

7. Qualifier
4Liquid Brachytherapy Radioisotope

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 92.20Infusion of liquid brachytherapy radioisotopeapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • No changes since FY2017.

Common questions about 3E0Q004

Is 3E0Q004 a valid ICD-10-PCS code for 2027?

Yes. 3E0Q004 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0Q004?

The CMS GEMs map 3E0Q004 to ICD-9-CM 92.20 (Infusion of liquid brachytherapy radioisotope).