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ICD-10-PCS 2027 procedure code

3E0N305Introduction of Other Antineoplastic into Male Reproductive, Percutaneous Approach

✓ Valid for 2027Male only

Short description: Introduce Oth Antineoplastic in Male Reprod, Perc

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0N305

3E0N305 is the ICD-10-PCS code for a introduction procedure on the male reproductive using a percutaneous approach with antineoplastic (qualifier: other antineoplastic). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to implantation of chemotherapeutic agent, the ICD-9-CM procedure title it maps to (00.10).

For a different body part, codes include 3E01305 (subcutaneous tissue), 3E02305 (muscle), 3E03305 (peripheral vein), 3E04305 (central vein), 3E05305 (peripheral artery), 3E06305 (central artery) and 21 more.

The same procedure with a different approach is coded 3E0N705 (via natural or artificial opening) and 3E0N805 (via natural or artificial opening endoscopic).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
NMale Reproductive
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Substance
0Antineoplastic

Includes: Amivantamab Monoclonal Antibody; Lurbinectedin; RYBREVANT (tm) (Amivantamab Monoclonal Antibody); ZEPZELCA(tm) (Lurbinectedin)

7. Qualifier
5Other Antineoplastic

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 00.10Implantation of chemotherapeutic agentapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0N305

Is 3E0N305 a valid ICD-10-PCS code for 2027?

Yes. 3E0N305 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0N305?

The CMS GEMs map 3E0N305 to ICD-9-CM 00.10 (Implantation of chemotherapeutic agent).