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ICD-10-PCS 2027 procedure code

3E0L329Introduction of Other Anti-infective into Pleural Cavity, Percutaneous Approach

✓ Valid for 2027

Short description: Introduce of Oth Anti-infect into Pleural Cav, Perc Approach

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0L329

3E0L329 is the ICD-10-PCS code for a introduction procedure on the pleural cavity using a percutaneous approach with anti-infective (qualifier: other anti-infective). In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection of antibiotic, the ICD-9-CM procedure title it maps to (99.21).

For a different body part, codes include 3E01329 (subcutaneous tissue), 3E02329 (muscle), 3E03329 (peripheral vein), 3E04329 (central vein), 3E05329 (peripheral artery), 3E06329 (central artery) and 20 more.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
LPleural Cavity
5. Approach
3Percutaneous

Entry, by puncture or minor incision, of instrumentation through the skin or mucous membrane and any other body layers necessary to reach the site of the procedure

6. Substance
2Anti-infective
7. Qualifier
9Other Anti-infective

Other versions of this procedure

Different qualifier

ICD-9-CM equivalent

Converter →
  • 99.21Injection of antibioticapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0L329

Is 3E0L329 a valid ICD-10-PCS code for 2027?

Yes. 3E0L329 is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0L329?

The CMS GEMs map 3E0L329 to ICD-9-CM 99.21 (Injection of antibiotic).