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ICD-10-PCS 2027 procedure code

3E0DXTZIntroduction of Destructive Agent into Mouth and Pharynx, External Approach

✓ Valid for 2027

Short description: Introduction of Destr Agent into Mouth/Phar, Extern Approach

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E0DXTZ

3E0DXTZ is the ICD-10-PCS code for a introduction procedure on the mouth and pharynx using an external approach with destructive agent. In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection or infusion of other therapeutic or prophylactic substance, the ICD-9-CM procedure title it maps to (99.29).

For a different body part, codes include 3E00XTZ (skin and mucous membranes), 3E09XTZ (nose), 3E0BXTZ (ear) and 3E0CXTZ (eye).

The same procedure with a different approach is coded 3E0D3TZ (percutaneous) and 3E0D7TZ (via natural or artificial opening).

With a different device, use 3E0DX3Z (anti-inflammatory), 3E0DX4Z (serum, toxoid and vaccine), 3E0DX6Z (nutritional substance), 3E0DX7Z (electrolytic and water balance substance), 3E0DXBZ (anesthetic agent), 3E0DXHZ (radioactive substance) and 3 more.

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
DMouth and Pharynx
5. Approach
XExternal

Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane

6. Substance
TDestructive Agent
7. Qualifier
ZNo Qualifier

Other versions of this procedure

ICD-9-CM equivalent

Converter →
  • 99.29Injection or infusion of other therapeutic or prophylactic substanceapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E0DXTZ

Is 3E0DXTZ a valid ICD-10-PCS code for 2027?

Yes. 3E0DXTZ is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E0DXTZ?

The CMS GEMs map 3E0DXTZ to ICD-9-CM 99.29 (Injection or infusion of other therapeutic or prophylactic substance).