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ICD-10-PCS 2027 procedure code

3E00X4ZIntroduction of Serum, Toxoid and Vaccine into Skin and Mucous Membranes, External Approach

✓ Valid for 2027

Short description: Introduce Serum/Tox/Vaccine in Skin/Mucous Mem, Extern

Code unchanged since ICD-10-PCS took effect on October 1, 2015. Source: official FY2027 ICD-10-PCS release from CMS. Page updated September 29, 2026. About our data

About 3E00X4Z

3E00X4Z is the ICD-10-PCS code for a introduction procedure on the skin and mucous membranes using an external approach with serum, toxoid and vaccine. In ICD-10-PCS, introduction means putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products.

In plain terms, this corresponds to injection or tattooing of skin lesion or defect, the ICD-9-CM procedure title it maps to (86.02).

For a different body part, codes include 3E09X4Z (nose) and 3E0DX4Z (mouth and pharynx).

With a different device, use 3E00X3Z (anti-inflammatory), 3E00XBZ (anesthetic agent), 3E00XKZ (other diagnostic substance), 3E00XMZ (pigment), 3E00XNZ (analgesics, hypnotics, sedatives) and 3E00XTZ (destructive agent).

It doesn't appear in the MS-DRG procedure index, so on its own it doesn't change the DRG assignment.

It has been valid since ICD-10-PCS took effect on October 1, 2015.

What each character means

1. Section
3Administration
2. Body System
EPhysiological Systems and Anatomical Regions
3. Operation
0Introduction

Putting in or on a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance except blood or blood products

4. Body System / Region
0Skin and Mucous Membranes
5. Approach
XExternal

Procedures performed directly on the skin or mucous membrane and procedures performed indirectly by the application of external force through the skin or mucous membrane

6. Substance
4Serum, Toxoid and Vaccine
7. Qualifier
ZNo Qualifier

Other versions of this procedure

Different body system / region

ICD-9-CM equivalent

Converter →
  • 86.02Injection or tattooing of skin lesion or defectapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about 3E00X4Z

Is 3E00X4Z a valid ICD-10-PCS code for 2027?

Yes. 3E00X4Z is valid for inpatient procedures from October 1, 2026 through September 30, 2027.

What is the ICD-9 procedure code for 3E00X4Z?

The CMS GEMs map 3E00X4Z to ICD-9-CM 86.02 (Injection or tattooing of skin lesion or defect).