ICD-10-CM 2027
ICD-10 code for Waldenström macroglobulinemia
Confirmed by the official ICD-10-CM index entry “disorder (of) › glomerular (in) › waldenström macroglobulinemia”. Page updated September 29, 2026.
About coding Waldenström macroglobulinemia
The ICD-10-CM code for Waldenström macroglobulinemia is C88.00 (Waldenstrom macroglobulinemia not having achieved remission). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on C88.00.
It is also searched as Waldenstrom macroglobulinemia, macroglobulinemia.
Within C88.0 (Waldenstrom macroglobulinemia), C88.00 is specifically for Waldenstrom macroglobulinemia not having achieved remission. Related codes cover in remission (C88.01).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Related Waldenström macroglobulinemia codes
- C88.01 Waldenstrom macroglobulinemia, in remission
Common questions about Waldenström macroglobulinemia ICD-10 codes
What is the ICD-10 code for Waldenström macroglobulinemia?
- C88.00 — Waldenstrom macroglobulinemia not having achieved remission. More specific codes apply when the documentation supports them: C88.01.
What is the ICD-10 code for waldenstrom macroglobulinemia, in remission?
- C88.01 — Waldenstrom macroglobulinemia, in remission.
Is C88.00 billable?
- Yes. C88.00 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C88.00 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C88.00 as a principal diagnosis.
Is C88.00 a CC or MCC?
- No. C88.00 is neither a CC nor an MCC under MS-DRG v44.0.