ICD-10-CM 2027
ICD-10 code for systemic sclerosis
From the official ICD-10-CM alphabetic index entry “Sclerosis, sclerotic › systemic”. Page updated September 29, 2026.
About coding systemic sclerosis
The ICD-10-CM code for systemic sclerosis is M34.9 (Systemic sclerosis, unspecified). The official index lists 7 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on M34.9.
Within M34, choose M34.9 (Systemic sclerosis, unspecified) only when documentation doesn't support a more specific option: progressive systemic sclerosis (M34.0), CR(E)ST syndrome (M34.1), systemic sclerosis induced by drug and chemical (M34.2) and other forms of systemic sclerosis (M34.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 545 (Connective Tissue Disorders with MCC, relative weight 2.3892), DRG 546 (Connective Tissue Disorders with CC, relative weight 1.1745) and DRG 547 (Connective Tissue Disorders without CC/MCC, relative weight 0.7526), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific systemic sclerosis codes (official index)
- with
- lung involvement M34.81 — Systemic sclerosis with lung involvement
- myopathy M34.82 — Systemic sclerosis with myopathy
- polyneuropathy M34.83 — Systemic sclerosis with polyneuropathy
- drug-induced M34.2 — Systemic sclerosis induced by drug and chemical
- due to chemicals NEC M34.2 — Systemic sclerosis induced by drug and chemical
- progressive M34.0 — Progressive systemic sclerosis
- specified NEC M34.89 — Other systemic sclerosis
Common questions about systemic sclerosis ICD-10 codes
What is the ICD-10 code for systemic sclerosis?
- M34.9 — Systemic sclerosis, unspecified. More specific codes apply when the documentation supports them: M34.81, M34.82, M34.83, M34.2 and others below.
What is the ICD-10 code for drug-induced systemic sclerosis?
- M34.2 — Systemic sclerosis induced by drug and chemical.
What is the ICD-10 code for progressive systemic sclerosis?
- M34.0 — Progressive systemic sclerosis.
Is M34.9 billable?
- Yes. M34.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can M34.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict M34.9 as a principal diagnosis.
Is M34.9 a CC or MCC?
- No. M34.9 is neither a CC nor an MCC under MS-DRG v44.0.