ICD-10-CM 2027
ICD-10 code for skin nonspecific eruption
From the official ICD-10-CM alphabetic index entry “Eruption › skin (nonspecific)”. Page updated September 29, 2026.
About coding skin nonspecific eruption
The ICD-10-CM code for skin nonspecific eruption is R21 (Rash and other nonspecific skin eruption). The official index lists 8 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R21.
Don't report R21 together with the conditions in its Excludes1 note: specified type of rash- code to condition and vesicular eruption (R23.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 606 (Minor Skin Disorders with MCC, relative weight 1.5728) and DRG 607 (Minor Skin Disorders without MCC, relative weight 0.8772), in MDC 09 (Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific skin nonspecific eruption codes (official index)
- creeping (meaning hookworm) B76.9 — Hookworm disease, unspecified
- due to inoculation/vaccination (generalized) L27.0 — Generalized skin eruption due to drugs and medicaments taken internally
- localized L27.1 — Localized skin eruption due to drugs and medicaments taken internally
- erysipeloid A26.0 — Cutaneous erysipeloid
- feigned L98.1 — Factitial dermatitis
- Kaposi's varicelliform B00.0 — Eczema herpeticum
- lichenoid L28.0 — Lichen simplex chronicus
- meaning dermatitis
- toxic NEC L53.0 — Toxic erythema
Don't confuse with (Excludes1 for R21)
- specified type of rash- code to condition
- vesicular eruption (R23.8)
Common questions about skin nonspecific eruption ICD-10 codes
What is the ICD-10 code for skin nonspecific eruption?
- R21 — Rash and other nonspecific skin eruption. More specific codes apply when the documentation supports them: B76.9, L27.0, L27.1, A26.0 and others below.
What is the ICD-10 code for creeping skin nonspecific eruption?
- B76.9 — Hookworm disease, unspecified.
What is the ICD-10 code for erysipeloid skin nonspecific eruption?
- A26.0 — Cutaneous erysipeloid.
What is the ICD-10 code for feigned skin nonspecific eruption?
- L98.1 — Factitial dermatitis.
What is the ICD-10 code for kaposi's varicelliform skin nonspecific eruption?
- B00.0 — Eczema herpeticum.
What is the ICD-10 code for lichenoid skin nonspecific eruption?
- L28.0 — Lichen simplex chronicus.
What is the ICD-10 code for toxic nec skin nonspecific eruption?
- L53.0 — Toxic erythema.
Is R21 billable?
- Yes. R21 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R21 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R21 as a principal diagnosis.
Is R21 a CC or MCC?
- No. R21 is neither a CC nor an MCC under MS-DRG v44.0.