ICD-10-CM 2027
ICD-10 code for salt or sodium depletion
From the official ICD-10-CM alphabetic index entry “Depletion › salt or sodium”. Page updated September 29, 2026.
About coding salt or sodium depletion
The ICD-10-CM code for salt or sodium depletion is E87.1 (Hypo-osmolality and hyponatremia). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E87.1.
Within E87 (other disorders of fluid, electrolyte and acid-base balance), E87.1 is specifically for Hypo-osmolality and hyponatremia. Related codes cover Hyperosmolality and hypernatremia (E87.0), acidosis (E87.2), Alkalosis (E87.3), mixed disorder of acid-base balance (E87.4), Hyperkalemia (E87.5), Hypokalemia (E87.6), fluid overload (E87.7) and other disorders of electrolyte and fluid balance, not elsewhere classified (E87.8).
Don't report E87.1 together with the conditions in its Excludes1 note: syndrome of inappropriate secretion of antidiuretic hormone (E22.2).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
More specific salt or sodium depletion codes (official index)
Don't confuse with (Excludes1 for E87.1)
- syndrome of inappropriate secretion of antidiuretic hormone (E22.2)
Common questions about salt or sodium depletion ICD-10 codes
What is the ICD-10 code for salt or sodium depletion?
- E87.1 — Hypo-osmolality and hyponatremia. More specific codes apply when the documentation supports them: T67.4, N28.9.
What is the ICD-10 code for nephropathy salt or sodium depletion?
- N28.9 — Disorder of kidney and ureter, unspecified.
Is E87.1 billable?
- Yes. E87.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E87.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E87.1 as a principal diagnosis.
Is E87.1 a CC or MCC?
- E87.1 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.