ICD-10-CM 2027
ICD-10 code for resistance
Choose a code from the options below based on the documentation.
From the official ICD-10-CM alphabetic index entry “Resistance, resistant (to)”. Page updated September 29, 2026.
About coding resistance
The official ICD-10-CM index doesn't give a single default code for resistance; the code depends on the details below.
More specific resistance codes (official index)
- activated protein C D68.51 — Activated protein C resistance
- insulin E88.819 — Insulin resistance, unspecified
- complicating pregnancy O26.89 — Other specified pregnancy related conditions
- specified type NEC E88.818 — Other insulin resistance
- organism (s)
- to
- drug Z16.30 — Resistance to unspecified antimicrobial drugs
- aminoglycosides Z16.29 — Resistance to other single specified antibiotic
- amoxicillin Z16.11 — Resistance to penicillins
- ampicillin Z16.11 — Resistance to penicillins
- antibiotic (s) Z16.20 — Resistance to unspecified antibiotic
- multiple Z16.24 — Resistance to multiple antibiotics
- specified NEC Z16.29 — Resistance to other single specified antibiotic
- antifungal Z16.32 — Resistance to antifungal drug(s)
- antimicrobial (single) Z16.30 — Resistance to unspecified antimicrobial drugs
- multiple Z16.35 — Resistance to multiple antimicrobial drugs
- specified NEC Z16.39 — Resistance to other specified antimicrobial drug
- antimycobacterial (single) Z16.341 — Resistance to single antimycobacterial drug
- multiple Z16.342 — Resistance to multiple antimycobacterial drugs
- antiparasitic Z16.31 — Resistance to antiparasitic drug(s)
- antiviral Z16.33 — Resistance to antiviral drug(s)
- beta lactam antibiotics Z16.10 — Resistance to unspecified beta lactam antibiotics
- specified NEC Z16.19 — Resistance to other specified beta lactam antibiotics
- carbapenem Z16.13 — Resistance to carbapenem
- cephalosporins Z16.19 — Resistance to other specified beta lactam antibiotics
- extended beta lactamase (ESBL) Z16.12 — Extended spectrum beta lactamase (ESBL) resistance
- fluoroquinolones Z16.23 — Resistance to quinolones and fluoroquinolones
- macrolides Z16.29 — Resistance to other single specified antibiotic
- methicillin
- multiple drugs (MDRO)
- antibiotics Z16.24 — Resistance to multiple antibiotics
- antimicrobial Z16.35 — Resistance to multiple antimicrobial drugs
- antimycobacterials Z16.342 — Resistance to multiple antimycobacterial drugs
- penicillins Z16.11 — Resistance to penicillins
- quinine (and related compounds) Z16.31 — Resistance to antiparasitic drug(s)
- quinolones Z16.23 — Resistance to quinolones and fluoroquinolones
- sulfonamides Z16.29 — Resistance to other single specified antibiotic
- tetracyclines Z16.29 — Resistance to other single specified antibiotic
- tuberculostatics (single) Z16.341 — Resistance to single antimycobacterial drug
- multiple Z16.342 — Resistance to multiple antimycobacterial drugs
- vancomycin Z16.21 — Resistance to vancomycin
- related antibiotics Z16.22 — Resistance to vancomycin related antibiotics
- thyroid hormone E07.89 — Other specified disorders of thyroid