ICD-10-CM 2027
ICD-10 code for reaction
Choose a code from the options below based on the documentation.
From the official ICD-10-CM alphabetic index entry “Reaction”. Page updated September 29, 2026.
About coding reaction
The official ICD-10-CM index doesn't give a single default code for reaction; the code depends on the details below.
More specific reaction codes (official index)
- adaptation
- adjustment (anxiety) (conduct disorder) (depressiveness) (distress)
- with
- mutism, elective (child) (adolescent) F94.0 — Selective mutism
- adverse
- food (any) (ingested) NEC T78.19 — Other adverse food reactions, not elsewhere classified
- anaphylactic
- affective
- allergic
- anaphylactic
- anaphylactoid
- anesthesia
- antitoxin (prophylactic) (therapeutic)
- anxiety F41.1 — Generalized anxiety disorder
- Arthus
- asthenic F48.8 — Other specified nonpsychotic mental disorders
- combat and operational stress F43.0 — Acute stress reaction
- compulsive F42.8 — Other obsessive-compulsive disorder
- conversion F44.9 — Dissociative and conversion disorder, unspecified
- crisis, acute F43.0 — Acute stress reaction
- deoxyribonuclease (DNA) (DNase) hypersensitivity D69.2 — Other nonthrombocytopenic purpura
- depressive (single episode) F32.9 — Major depressive disorder, single episode, unspecified
- affective (single episode) F31.4 — Bipolar disorder, current episode depressed, severe, without psychotic features
- recurrent episode F33.9 — Major depressive disorder, recurrent, unspecified
- neurotic F34.1 — Dysthymic disorder
- psychoneurotic F34.1 — Dysthymic disorder
- psychotic F32.3 — Major depressive disorder, single episode, severe with psychotic features
- recurrent
- dissociative F44.9 — Dissociative and conversion disorder, unspecified
- drug NEC T88.7 — Unspecified adverse effect of drug or medicament
- addictive
- transmitted via placenta or breast milk
- allergic
- lichenoid L43.2 — Lichenoid drug reaction
- newborn P93.8 — Other reactions and intoxications due to drugs administered to newborn
- gray baby syndrome P93.0 — Grey baby syndrome
- overdose or poisoning (by accident)
- photoallergic L56.1 — Drug photoallergic response
- phototoxic L56.0 — Drug phototoxic response
- withdrawal
- infant of dependent mother P96.1 — Neonatal withdrawal symptoms from maternal use of drugs of addiction
- newborn P96.1 — Neonatal withdrawal symptoms from maternal use of drugs of addiction
- wrong substance given or taken (by accident)
- fear F40.9 — Phobic anxiety disorder, unspecified
- child (abnormal) F93.8 — Other childhood emotional disorders
- febrile nonhemolytic transfusion (FNHTR) R50.84 — Febrile nonhemolytic transfusion reaction
- fluid loss, cerebrospinal G97.1 — Other reaction to spinal and lumbar puncture
- foreign
- body NEC
- in operative wound (inadvertently left)
- substance accidentally left during a procedure (chemical) (powder) (talc) T81.60 — Unspecified acute reaction to foreign substance accidentally left during a procedure
- aseptic peritonitis T81.61 — Aseptic peritonitis due to foreign substance accidentally left during a procedure
- body or object (instrument) (sponge) (swab)
- specified reaction NEC T81.69 — Other acute reaction to foreign substance accidentally left during a procedure
- grief
- Herxheimer's R68.89 — Other general symptoms and signs
- hyperkinetic
- hypochondriacal F45.20 — Hypochondriacal disorder, unspecified
- hypoglycemic, due to insulin E16.0 — Drug-induced hypoglycemia without coma
- with coma (diabetic)
- nondiabetic E15 — Nondiabetic hypoglycemic coma
- therapeutic misadventure
- hypomanic F30.8 — Other manic episodes
- hysterical F44.9 — Dissociative and conversion disorder, unspecified
- immunization
- incompatibility
- ABO blood group (infusion) (transfusion)
- delayed serologic T80.39 — Other ABO incompatibility reaction due to transfusion of blood or blood products
- minor blood group (Duffy) (E) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S) T80.89 — Other complications following infusion, transfusion and therapeutic injection
- Rh (factor) (infusion) (transfusion)
- inflammatory
- infusion
- inoculation (immune serum)
- insulin T38.3 — Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs
- involutional psychotic
- leukemoid D72.823 — Leukemoid reaction
- basophilic D72.823 — Leukemoid reaction
- lymphocytic D72.823 — Leukemoid reaction
- monocytic D72.823 — Leukemoid reaction
- myelocytic D72.823 — Leukemoid reaction
- neutrophilic D72.823 — Leukemoid reaction
- LSD (acute)
- due to drug abuse
- due to drug dependence
- lumbar puncture G97.1 — Other reaction to spinal and lumbar puncture
- manic-depressive
- neurasthenic F48.8 — Other specified nonpsychotic mental disorders
- neurogenic
- neurotic F48.9 — Nonpsychotic mental disorder, unspecified
- neurotic-depressive F34.1 — Dysthymic disorder
- nitritoid
- nonspecific
- to
- cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis R76.12 — Nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis
- QuantiFERON-TB test (QFT) without active tuberculosis R76.12 — Nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis
- tuberculin test R76.11 — Nonspecific reaction to tuberculin skin test without active tuberculosis
- obsessive-compulsive F42.8 — Other obsessive-compulsive disorder
- organic, acute or subacute
- paranoid (acute) F23 — Brief psychotic disorder
- chronic F22 — Delusional disorders
- senile F03 — Unspecified dementia
- passive dependency F60.7 — Dependent personality disorder
- phobic F40.9 — Phobic anxiety disorder, unspecified
- post-traumatic stress, uncomplicated Z73.3 — Stress, not elsewhere classified
- psychogenic F99 — Mental disorder, not otherwise specified
- psychoneurotic
- compulsive F42.8 — Other obsessive-compulsive disorder
- depersonalization F48.1 — Depersonalization-derealization syndrome
- depressive F34.1 — Dysthymic disorder
- hypochondriacal F45.20 — Hypochondriacal disorder, unspecified
- neurasthenic F48.8 — Other specified nonpsychotic mental disorders
- obsessive F42.8 — Other obsessive-compulsive disorder
- psychophysiologic
- psychosomatic
- psychotic
- scarlet fever toxin
- schizophrenic F23 — Brief psychotic disorder
- acute (brief) (undifferentiated) F23 — Brief psychotic disorder
- latent F21 — Schizotypal disorder
- undifferentiated (acute) (brief) F23 — Brief psychotic disorder
- serological for syphilis
- serum T80.69 — Other serum reaction due to other serum
- anaphylactic (immediate) T80.59 — Anaphylactic reaction due to other serum
- specified reaction NEC
- due to
- administration of blood and blood products T80.61 — Other serum reaction due to administration of blood and blood products
- immunization T80.62 — Other serum reaction due to vaccination
- serum specified NEC T80.69 — Other serum reaction due to other serum
- vaccination T80.62 — Other serum reaction due to vaccination
- situational
- somatization
- spinal puncture G97.1 — Other reaction to spinal and lumbar puncture
- dural G97.1 — Other reaction to spinal and lumbar puncture
- stress (severe) F43.9 — Reaction to severe stress, unspecified
- acute (agitation) ("daze") (disorientation) (disturbance of consciousness) (flight reaction) (fugue) F43.0 — Acute stress reaction
- specified NEC F43.89 — Other reactions to severe stress
- surgical procedure
- tetanus antitoxin
- toxic, to local anesthesia T88.59 — Other complications of anesthesia
- in labor and delivery O74.4 — Toxic reaction to local anesthesia during labor and delivery
- in pregnancy O29.3X — Toxic reaction to local anesthesia during pregnancy
- postpartum, puerperal O89.3 — Toxic reaction to local anesthesia during the puerperium
- toxin-antitoxin
- transfusion (blood) (bone marrow) (lymphocytes) (allergic)
- tuberculin skin test, abnormal R76.11 — Nonspecific reaction to tuberculin skin test without active tuberculosis
- vaccination (any)
- withdrawing, child or adolescent F93.8 — Other childhood emotional disorders
Common questions about reaction ICD-10 codes
What is the ICD-10 code for anxiety reaction?
- F41.1 — Generalized anxiety disorder.
What is the ICD-10 code for asthenic reaction?
- F48.8 — Other specified nonpsychotic mental disorders.
What is the ICD-10 code for combat and operational stress reaction?
- F43.0 — Acute stress reaction.
What is the ICD-10 code for compulsive reaction?
- F42.8 — Other obsessive-compulsive disorder.
What is the ICD-10 code for conversion reaction?
- F44.9 — Dissociative and conversion disorder, unspecified.
What is the ICD-10 code for deoxyribonuclease hypersensitivity reaction?
- D69.2 — Other nonthrombocytopenic purpura.
What is the ICD-10 code for depressive reaction?
- F32.9 — Major depressive disorder, single episode, unspecified.