ICD-10-CM 2027
ICD-10 code for polyglandular hyperfunction
From the official ICD-10-CM alphabetic index entry “Hyperfunction › polyglandular”. Page updated September 29, 2026.
About coding polyglandular hyperfunction
The ICD-10-CM code for polyglandular hyperfunction is E31.1 (Polyglandular hyperfunction).
Within E31 (polyglandular dysfunction), E31.1 is specifically for polyglandular hyperfunction. Related codes cover autoimmune polyglandular failure (E31.0), multiple endocrine neoplasia [MEN] syndromes (E31.2), other polyglandular dysfunction (E31.8) and unspecified (E31.9).
Don't report E31.1 together with the conditions in its Excludes1 note: multiple endocrine adenomatosis (E31.2-) and multiple endocrine neoplasia (E31.2-).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for E31.1)
Common questions about polyglandular hyperfunction ICD-10 codes
What is the ICD-10 code for polyglandular hyperfunction?
- E31.1 — Polyglandular hyperfunction.
Is E31.1 billable?
- Yes. E31.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E31.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E31.1 as a principal diagnosis.
Is E31.1 a CC or MCC?
- No. E31.1 is neither a CC nor an MCC under MS-DRG v44.0.