ICD-10-CM 2027
ICD-10 code for PANS
Other specified disorders involving the immune mechanism, not elsewhere classified
From the official ICD-10-CM alphabetic index entry “PANS (Pediatric Acute-onset Neuropsychiatric Syndrome)”. Page updated September 29, 2026.
About coding PANS
The ICD-10-CM code for PANS is D89.89 (Other specified disorders involving the immune mechanism, not elsewhere classified).
Within D89.8, choose D89.89 (Other specified disorders involving the immune mechanism, not elsewhere classified) only when documentation doesn't support a more specific option: graft-versus-host disease (D89.81), autoimmune lymphoproliferative syndrome [ALPS] (D89.82), Cytokine release syndrome (D89.83) and IgG4-related disease (D89.84).
Don't report D89.89 together with the conditions in its Excludes1 note: human immunodeficiency virus disease (B20).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for D89.89)
- human immunodeficiency virus disease (B20)
Common questions about PANS ICD-10 codes
What is the ICD-10 code for PANS?
- D89.89 — Other specified disorders involving the immune mechanism, not elsewhere classified.
Is D89.89 billable?
- Yes. D89.89 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D89.89 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D89.89 as a principal diagnosis.
Is D89.89 a CC or MCC?
- No. D89.89 is neither a CC nor an MCC under MS-DRG v44.0.