ICD-10-CM 2027
ICD-10 code for Osteosclerosis
From the official ICD-10-CM alphabetic index entry “Osteosclerosis”. Page updated September 29, 2026.
About coding Osteosclerosis
The ICD-10-CM code for Osteosclerosis is Q78.2 (Osteopetrosis). The official index lists 4 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on Q78.2.
Within Q78 (other osteochondrodysplasias), Q78.2 is specifically for Osteopetrosis. Related codes cover Osteogenesis imperfecta (Q78.0), Polyostotic fibrous dysplasia (Q78.1), progressive diaphyseal dysplasia (Q78.3), Enchondromatosis (Q78.4), Metaphyseal dysplasia (Q78.5), multiple congenital exostoses (Q78.6), other specified osteochondrodysplasias (Q78.8) and osteochondrodysplasia, unspecified (Q78.9).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 564 (Other Musculoskeletal System and Connective Tissue Diagnoses with MCC, relative weight 1.4908), DRG 565 (Other Musculoskeletal System and Connective Tissue Diagnoses with CC, relative weight 0.9783) and DRG 566 (Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCC, relative weight 0.7378), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Osteosclerosis codes (official index)
Common questions about Osteosclerosis ICD-10 codes
What is the ICD-10 code for Osteosclerosis?
- Q78.2 — Osteopetrosis. More specific codes apply when the documentation supports them: M85.8, Q77.4, Q78.2, D75.81.
What is the ICD-10 code for acquired osteosclerosis?
- M85.8 — Other specified disorders of bone density and structure (header code; choose a more specific subcode).
What is the ICD-10 code for congenita osteosclerosis?
- Q77.4 — Achondroplasia.
What is the ICD-10 code for fragilitas osteosclerosis?
- Q78.2 — Osteopetrosis.
What is the ICD-10 code for myelofibrosis osteosclerosis?
- D75.81 — Myelofibrosis.
Is Q78.2 billable?
- Yes. Q78.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Q78.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict Q78.2 as a principal diagnosis.
Is Q78.2 a CC or MCC?
- Q78.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.