ICD-10-CM 2027
ICD-10 code for osteolysis
From the official ICD-10-CM alphabetic index entry “Osteolysis”. Page updated September 29, 2026.
About coding osteolysis
The ICD-10-CM code for osteolysis is M89.50 (Osteolysis, unspecified site). The official index lists 22 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on M89.50.
Within M89.5, choose M89.50 (unspecified site) only when documentation doesn't support a more specific option: shoulder (M89.51), upper arm (M89.52), forearm (M89.53), hand (M89.54), thigh (M89.55), lower leg (M89.56), ankle and foot (M89.57), other site (M89.58) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 564 (Other Musculoskeletal System and Connective Tissue Diagnoses with MCC, relative weight 1.4908), DRG 565 (Other Musculoskeletal System and Connective Tissue Diagnoses with CC, relative weight 0.9783) and DRG 566 (Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCC, relative weight 0.7378), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific osteolysis codes (official index)
- carpus M89.54 — Osteolysis, hand
- clavicle M89.51 — Osteolysis, shoulder
- femur M89.55 — Osteolysis, thigh
- fibula M89.56 — Osteolysis, lower leg
- finger M89.54 — Osteolysis, hand
- humerus M89.52 — Osteolysis, upper arm
- ilium M89.58 — Osteolysis, other site
- ischium M89.58 — Osteolysis, other site
- joint prosthesis (periprosthetic)
- metacarpus M89.54 — Osteolysis, hand
- metatarsus M89.57 — Osteolysis, ankle and foot
- multiple sites M89.59 — Osteolysis, multiple sites
- neck M89.58 — Osteolysis, other site
- periprosthetic
- pubic ramus [pubis] M89.58 — Osteolysis, other site
- radius M89.53 — Osteolysis, forearm
- rib M89.58 — Osteolysis, other site
- scapula M89.51 — Osteolysis, shoulder
- skull M89.58 — Osteolysis, other site
- tarsus M89.57 — Osteolysis, ankle and foot
- tibia M89.56 — Osteolysis, lower leg
- toe M89.57 — Osteolysis, ankle and foot
- ulna M89.53 — Osteolysis, forearm
- vertebra M89.58 — Osteolysis, other site
Common questions about osteolysis ICD-10 codes
What is the ICD-10 code for osteolysis?
- M89.50 — Osteolysis, unspecified site. More specific codes apply when the documentation supports them: M89.54, M89.51, M89.55, M89.56 and others below.
What is the ICD-10 code for carpus osteolysis?
- M89.54 — Osteolysis, hand (header code; choose a more specific subcode).
What is the ICD-10 code for clavicle osteolysis?
- M89.51 — Osteolysis, shoulder (header code; choose a more specific subcode).
What is the ICD-10 code for femur osteolysis?
- M89.55 — Osteolysis, thigh (header code; choose a more specific subcode).
What is the ICD-10 code for fibula osteolysis?
- M89.56 — Osteolysis, lower leg (header code; choose a more specific subcode).
What is the ICD-10 code for finger osteolysis?
- M89.54 — Osteolysis, hand (header code; choose a more specific subcode).
What is the ICD-10 code for humerus osteolysis?
- M89.52 — Osteolysis, upper arm (header code; choose a more specific subcode).
Is M89.50 billable?
- Yes. M89.50 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can M89.50 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict M89.50 as a principal diagnosis.
Is M89.50 a CC or MCC?
- No. M89.50 is neither a CC nor an MCC under MS-DRG v44.0.