ICD-10-CM 2027
ICD-10 code for Nephrosis
Nephrotic syndrome with unspecified morphologic changes
From the official ICD-10-CM alphabetic index entry “Nephrosis, nephrotic (Epstein's) (syndrome) (congenital)”. Page updated September 29, 2026.
About coding Nephrosis
The ICD-10-CM code for Nephrosis is N04.9 (Nephrotic syndrome with unspecified morphologic changes). The official index lists 20 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on N04.9.
Within N04, choose N04.9 (with unspecified morphologic changes) only when documentation doesn't support a more specific option: with minor glomerular abnormality (N04.0), with focal and segmental glomerular lesions (N04.1), with diffuse membranous glomerulonephritis (N04.2), with diffuse mesangial proliferative glomerulonephritis (N04.3), with diffuse endocapillary proliferative glomerulonephritis (N04.4), with diffuse mesangiocapillary glomerulonephritis (N04.5), with dense deposit disease (N04.6), with diffuse crescentic glomerulonephritis (N04.7) and 3 more.
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 698 (Other Kidney and Urinary Tract Diagnoses with MCC, relative weight 1.6398), DRG 699 (Other Kidney and Urinary Tract Diagnoses with CC, relative weight 1.0003) and DRG 700 (Other Kidney and Urinary Tract Diagnoses without CC/MCC, relative weight 0.6741), in MDC 11 (Diseases and Disorders of the Kidney and Urinary Tract), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Nephrosis codes (official index)
- with
- foot process disease N04.9 — Nephrotic syndrome with unspecified morphologic changes
- glomerular lesion N04.1 — Nephrotic syndrome with focal and segmental glomerular lesions
- hypocomplementemic N04.5 — Nephrotic syndrome with diffuse mesangiocapillary glomerulonephritis
- acute N04.9 — Nephrotic syndrome with unspecified morphologic changes
- anoxic
- chemical
- cholemic K76.7 — Hepatorenal syndrome
- diabetic
- Finnish type (congenital) Q89.89 — Other specified congenital malformations
- hemoglobin N10 — Acute pyelonephritis
- hemoglobinuric
- in
- amyloidosis E85.4 — Organ-limited amyloidosis
- diabetes mellitus
- epidemic hemorrhagic fever A98.5 — Hemorrhagic fever with renal syndrome
- malaria (malariae) B52.0 — Plasmodium malariae malaria with nephropathy
- ischemic
- lipoid N04.9 — Nephrotic syndrome with unspecified morphologic changes
- lower nephron
- malarial (malariae) B52.0 — Plasmodium malariae malaria with nephropathy
- minimal change N04.0 — Nephrotic syndrome with minor glomerular abnormality
- myoglobin N10 — Acute pyelonephritis
- necrotizing
- osmotic (sucrose) N25.89 — Other disorders resulting from impaired renal tubular function
- radiation N04.9 — Nephrotic syndrome with unspecified morphologic changes
- syphilitic (late) A52.75 — Syphilis of kidney and ureter
- toxic
- tubular (acute) N17.0 — Acute kidney failure with tubular necrosis
- postprocedural N99.0 — Postprocedural (acute) (chronic) kidney failure
- radiation N04.9 — Nephrotic syndrome with unspecified morphologic changes
Common questions about Nephrosis ICD-10 codes
What is the ICD-10 code for Nephrosis?
- N04.9 — Nephrotic syndrome with unspecified morphologic changes. More specific codes apply when the documentation supports them: N04.9, N04.1, N04.5, N04.9 and others below.
What is the ICD-10 code for acute nephrosis?
- N04.9 — Nephrotic syndrome with unspecified morphologic changes.
What is the ICD-10 code for cholemic nephrosis?
- K76.7 — Hepatorenal syndrome.
What is the ICD-10 code for finnish type nephrosis?
- Q89.89 — Other specified congenital malformations.
What is the ICD-10 code for hemoglobin nephrosis?
- N10 — Acute pyelonephritis.
What is the ICD-10 code for lipoid nephrosis?
- N04.9 — Nephrotic syndrome with unspecified morphologic changes.
What is the ICD-10 code for malarial nephrosis?
- B52.0 — Plasmodium malariae malaria with nephropathy.
Is N04.9 billable?
- Yes. N04.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can N04.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict N04.9 as a principal diagnosis.
Is N04.9 a CC or MCC?
- N04.9 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.