ICD-10-CM 2027
ICD-10 code for myelosuppressive agent long-term drug therapy
From the official ICD-10-CM alphabetic index entry “Long-term (current) (prophylactic) drug therapy (use of) › myelosuppressive agent”. Page updated September 29, 2026.
About coding myelosuppressive agent long-term drug therapy
The ICD-10-CM code for myelosuppressive agent long-term drug therapy is Z79.64 (Long term (current) use of myelosuppressive agent).
Within Z79.6 (long term (current) use of immunomodulators and immunosuppressants), Z79.64 is specifically for long term (current) use of myelosuppressive agent. Related codes cover unspecified immunomodulators and immunosuppressants (Z79.60), immunomodulator (Z79.61), immunosuppressant (Z79.62), chemotherapeutic agent (Z79.63) and other immunomodulators and immunosuppressants (Z79.69).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 949 (Aftercare with CC/MCC, relative weight 1.123) and DRG 950 (Aftercare without CC/MCC, relative weight 0.7664), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about myelosuppressive agent long-term drug therapy ICD-10 codes
What is the ICD-10 code for myelosuppressive agent long-term drug therapy?
- Z79.64 — Long term (current) use of myelosuppressive agent.
Is Z79.64 billable?
- Yes. Z79.64 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z79.64 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z79.64 a CC or MCC?
- No. Z79.64 is neither a CC nor an MCC under MS-DRG v44.0.