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ICD-10-CM 2027

ICD-10 code for mutation

Choose a code from the options below based on the documentation.

From the official ICD-10-CM alphabetic index entry “Mutation (s)”. Page updated September 29, 2026.

About coding mutation

The official ICD-10-CM index doesn't give a single default code for mutation; the code depends on the details below.

More specific mutation codes (official index)

  • factor V Leiden D68.51 — Activated protein C resistance
  • surfactant, of lung J84.83 — Surfactant mutations of the lung
  • prothrombin gene D68.52 — Prothrombin gene mutation

Common questions about mutation ICD-10 codes

What is the ICD-10 code for factor v leiden mutation?

D68.51 — Activated protein C resistance.

What is the ICD-10 code for prothrombin gene mutation?

D68.52 — Prothrombin gene mutation.