ICD-10-CM 2027
ICD-10 code for malignant mast cell neoplasm
From the official ICD-10-CM alphabetic index entry “Neoplasm, neoplastic › malignant mast cell”. Page updated September 29, 2026.
About coding malignant mast cell neoplasm
The ICD-10-CM code for malignant mast cell neoplasm is C96.20 (Malignant mast cell neoplasm, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on C96.20.
Within C96.2, choose C96.20 (unspecified) only when documentation doesn't support a more specific option: aggressive systemic mastocytosis (C96.21), mast cell sarcoma (C96.22) and other malignant mast cell neoplasm (C96.29).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 011 (Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC, relative weight 5.6154), DRG 012 (Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC, relative weight 4.381), DRG 013 (Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC, relative weight 2.7307), DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272) and 6 more, in Pre-MDC and MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific malignant mast cell neoplasm codes (official index)
- specified type NEC C96.29 — Other malignant mast cell neoplasm
Common questions about malignant mast cell neoplasm ICD-10 codes
What is the ICD-10 code for malignant mast cell neoplasm?
- C96.20 — Malignant mast cell neoplasm, unspecified. More specific codes apply when the documentation supports them: C96.29.
Is C96.20 billable?
- Yes. C96.20 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C96.20 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C96.20 as a principal diagnosis.
Is C96.20 a CC or MCC?
- C96.20 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.