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ICD-10-CM 2027

ICD-10 code for lymphoproliferative disease

D47.9

Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Disease, diseased › lymphoproliferative”. Page updated September 29, 2026.

About coding lymphoproliferative disease

The ICD-10-CM code for lymphoproliferative disease is D47.9 (Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified). The official index lists 3 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D47.9.

Within D47, choose D47.9 (Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified) only when documentation doesn't support a more specific option: mast cell neoplasms of uncertain behavior (D47.0), chronic myeloproliferative disease (D47.1), monoclonal gammopathy (D47.2), essential (hemorrhagic) thrombocythemia (D47.3), Osteomyelofibrosis (D47.4) and other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue (D47.Z).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

More specific lymphoproliferative disease codes (official index)

  • specified NEC D47.Z9 — Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
  • T-gamma D47.Z9 — Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
  • X-linked D82.3 — Immunodeficiency following hereditary defective response to Epstein-Barr virus

Common questions about lymphoproliferative disease ICD-10 codes

What is the ICD-10 code for lymphoproliferative disease?

D47.9 — Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified. More specific codes apply when the documentation supports them: D47.Z9, D47.Z9, D82.3.

What is the ICD-10 code for t-gamma lymphoproliferative disease?

D47.Z9 — Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue.

What is the ICD-10 code for x-linked lymphoproliferative disease?

D82.3 — Immunodeficiency following hereditary defective response to Epstein-Barr virus.

Is D47.9 billable?

Yes. D47.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D47.9 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D47.9 as a principal diagnosis.

Is D47.9 a CC or MCC?

D47.9 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.