ICD-10-CM 2027
ICD-10 code for LTBI
From the official ICD-10-CM alphabetic index entry “LTBI (latent tuberculosis infection)”. Page updated September 29, 2026.
About coding LTBI
The ICD-10-CM code for LTBI is Z22.7 (Latent tuberculosis).
Within Z22 (carrier of infectious disease), Z22.7 is specifically for latent tuberculosis. Related codes cover carrier of typhoid (Z22.0), carrier of other intestinal infectious diseases (Z22.1), carrier of diphtheria (Z22.2), carrier of other specified bacterial diseases (Z22.3), carrier of infections with a predominantly sexual mode of transmission (Z22.4), carrier of human T-lymphotropic virus type-1 [HTLV-1] infection (Z22.6), carrier of other infectious diseases (Z22.8) and unspecified (Z22.9).
Don't report Z22.7 together with the conditions in its Excludes1 note: nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis (R76.12) and nonspecific reaction to tuberculin skin test without active tuberculosis (R76.11).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for Z22.7)
Common questions about LTBI ICD-10 codes
What is the ICD-10 code for LTBI?
- Z22.7 — Latent tuberculosis.
Is Z22.7 billable?
- Yes. Z22.7 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z22.7 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z22.7 a CC or MCC?
- No. Z22.7 is neither a CC nor an MCC under MS-DRG v44.0.