ICD-10-CM 2027
ICD-10 code for liver cholangiocarcinoma
From the official ICD-10-CM alphabetic index entry “Cholangiocarcinoma › liver”. Page updated September 29, 2026.
About coding liver cholangiocarcinoma
The ICD-10-CM code for liver cholangiocarcinoma is C22.1 (Intrahepatic bile duct carcinoma).
Within C22 (malignant neoplasm of liver and intrahepatic bile ducts), C22.1 is specifically for intrahepatic bile duct carcinoma. Related codes cover liver cell carcinoma (C22.0), Hepatoblastoma (C22.2), Angiosarcoma of liver (C22.3), other sarcomas of liver (C22.4), other specified carcinomas of liver (C22.7), malignant neoplasm of liver, primary, unspecified as to type (C22.8) and malignant neoplasm of liver, not specified as primary or secondary (C22.9).
Don't report C22.1 together with the conditions in its Excludes1 note: malignant neoplasm of hepatic duct (C24.0).
Use an additional code to identify: alcohol abuse and dependence (F10.-), hepatitis B (B16.-, B18.0-B18.1) and hepatitis C (B17.1-, B18.2).
Don't confuse with (Excludes1 for C22.1)
- malignant neoplasm of hepatic duct (C24.0)
Common questions about liver cholangiocarcinoma ICD-10 codes
What is the ICD-10 code for liver cholangiocarcinoma?
- C22.1 — Intrahepatic bile duct carcinoma.
Is C22.1 billable?
- Yes. C22.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C22.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C22.1 as a principal diagnosis.
Is C22.1 a CC or MCC?
- C22.1 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.