ICD-10-CM 2027
ICD-10 code for leukocytes decrease
From the official ICD-10-CM alphabetic index entry “Decrease (d) › leukocytes”. Page updated September 29, 2026.
About coding leukocytes decrease
The ICD-10-CM code for leukocytes decrease is D72.819 (Decreased white blood cell count, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on D72.819.
Within D72.81, choose D72.819 (unspecified) only when documentation doesn't support a more specific option: Lymphocytopenia (D72.810) and other decreased white blood cell count (D72.818).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific leukocytes decrease codes (official index)
- specified NEC D72.818 — Other decreased white blood cell count
Common questions about leukocytes decrease ICD-10 codes
What is the ICD-10 code for leukocytes decrease?
- D72.819 — Decreased white blood cell count, unspecified. More specific codes apply when the documentation supports them: D72.818.
Is D72.819 billable?
- Yes. D72.819 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D72.819 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D72.819 as a principal diagnosis.
Is D72.819 a CC or MCC?
- No. D72.819 is neither a CC nor an MCC under MS-DRG v44.0.