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ICD-10-CM 2027

ICD-10 code for inspissated bile syndrome

P59.1

Inspissated bile syndrome

From the official ICD-10-CM alphabetic index entry “Inspissated bile syndrome (newborn)”. Page updated September 29, 2026.

About coding inspissated bile syndrome

The ICD-10-CM code for inspissated bile syndrome is P59.1 (Inspissated bile syndrome).

Within P59 (neonatal jaundice from other and unspecified causes), P59.1 is specifically for inspissated bile syndrome. Related codes cover neonatal jaundice associated with preterm delivery (P59.0), neonatal jaundice from other and unspecified hepatocellular damage (P59.2), neonatal jaundice from breast milk inhibitor (P59.3), neonatal jaundice from other specified causes (P59.8) and neonatal jaundice, unspecified (P59.9).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about inspissated bile syndrome ICD-10 codes

What is the ICD-10 code for inspissated bile syndrome?

P59.1 — Inspissated bile syndrome.

Is P59.1 billable?

Yes. P59.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can P59.1 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict P59.1 as a principal diagnosis.

Is P59.1 a CC or MCC?

P59.1 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.