ICD-10-CM 2027
ICD-10 code for hypoglycemia
Confirmed by the official ICD-10-CM index entry “hypoglycemia (spontaneous)”. Page updated September 29, 2026.
About coding hypoglycemia
The ICD-10-CM code for hypoglycemia is E16.2 (Hypoglycemia, unspecified). The official index lists 9 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E16.2.
It is also searched as low blood sugar.
Within E16, choose E16.2 (Hypoglycemia, unspecified) only when documentation doesn't support a more specific option: drug-induced hypoglycemia without coma (E16.0), other hypoglycemia (E16.1), increased secretion of glucagon (E16.3), increased secretion of gastrin (E16.4), other specified disorders of pancreatic internal secretion (E16.8), disorder of pancreatic internal secretion, unspecified (E16.9) and hypoglycemia level (E16.A).
Don't report E16.2 together with the conditions in its Excludes1 note: diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649).
Use an additional code for hypoglycemia level, if applicable (E16.A-).
Related Hypoglycemia codes
- E16.0 Drug-induced hypoglycemia without coma
- E16.1 Other hypoglycemia
- E16.3 Increased secretion of glucagon
- E16.4 Increased secretion of gastrin
- E16.8 Other specified disorders of pancreatic internal secretion
- E16.9 Disorder of pancreatic internal secretion, unspecified
- E16.A1 Hypoglycemia level 1
- E16.A2 Hypoglycemia level 2
- E16.A3 Hypoglycemia level 3
Don't confuse with (Excludes1 for E16.2)
Common questions about hypoglycemia ICD-10 codes
What is the ICD-10 code for hypoglycemia?
- E16.2 — Hypoglycemia, unspecified. More specific codes apply when the documentation supports them: E16.0, E16.1, E16.3, E16.4 and others below.
What is the ICD-10 code for drug-induced hypoglycemia without coma?
- E16.0 — Drug-induced hypoglycemia without coma.
What is the ICD-10 code for other hypoglycemia?
- E16.1 — Other hypoglycemia.
What is the ICD-10 code for increased secretion of glucagon?
- E16.3 — Increased secretion of glucagon.
What is the ICD-10 code for increased secretion of gastrin?
- E16.4 — Increased secretion of gastrin.
What is the ICD-10 code for other specified disorders of pancreatic internal secretion?
- E16.8 — Other specified disorders of pancreatic internal secretion.
What is the ICD-10 code for disorder of pancreatic internal secretion, unspecified?
- E16.9 — Disorder of pancreatic internal secretion, unspecified.
Is E16.2 billable?
- Yes. E16.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E16.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E16.2 as a principal diagnosis.
Is E16.2 a CC or MCC?
- No. E16.2 is neither a CC nor an MCC under MS-DRG v44.0.