Skip to content
Dx

ICD-10-CM 2027

ICD-10 code for Hyperproteinemia

E88.09

Other disorders of plasma-protein metabolism, not elsewhere classified

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Hyperproteinemia”. Page updated September 29, 2026.

About coding Hyperproteinemia

The ICD-10-CM code for Hyperproteinemia is E88.09 (Other disorders of plasma-protein metabolism, not elsewhere classified).

Within E88.0, choose E88.09 (Other disorders of plasma-protein metabolism, not elsewhere classified) only when documentation doesn't support a more specific option: Alpha-1-antitrypsin deficiency (E88.01) and Plasminogen deficiency (E88.02).

Use an additional code for: codes for associated conditions.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

Common questions about Hyperproteinemia ICD-10 codes

What is the ICD-10 code for Hyperproteinemia?

E88.09 — Other disorders of plasma-protein metabolism, not elsewhere classified.

Is E88.09 billable?

Yes. E88.09 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E88.09 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E88.09 as a principal diagnosis.

Is E88.09 a CC or MCC?

No. E88.09 is neither a CC nor an MCC under MS-DRG v44.0.