ICD-10-CM 2027
ICD-10 code for Hyperinsulinism
From the official ICD-10-CM alphabetic index entry “Hyperinsulinism (functional)”. Page updated September 29, 2026.
About coding Hyperinsulinism
The ICD-10-CM code for Hyperinsulinism is E16.1 (Other hypoglycemia). The official index lists 3 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E16.1.
Within E16, choose E16.1 (Other hypoglycemia) only when documentation doesn't support a more specific option: drug-induced hypoglycemia without coma (E16.0), hypoglycemia, unspecified (E16.2), increased secretion of glucagon (E16.3), increased secretion of gastrin (E16.4), other specified disorders of pancreatic internal secretion (E16.8), disorder of pancreatic internal secretion, unspecified (E16.9) and hypoglycemia level (E16.A).
Don't report E16.1 together with the conditions in its Excludes1 note: diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649), hypoglycemia in infant of diabetic mother (P70.1) and neonatal hypoglycemia (P70.4).
Use an additional code for hypoglycemia level, if applicable (E16.A-).
More specific Hyperinsulinism codes (official index)
Don't confuse with (Excludes1 for E16.1)
Common questions about Hyperinsulinism ICD-10 codes
What is the ICD-10 code for Hyperinsulinism?
- E16.1 — Other hypoglycemia. More specific codes apply when the documentation supports them: E15, E16.1, E16.1.
What is the ICD-10 code for ectopic hyperinsulinism?
- E16.1 — Other hypoglycemia.
Is E16.1 billable?
- Yes. E16.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E16.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E16.1 as a principal diagnosis.
Is E16.1 a CC or MCC?
- No. E16.1 is neither a CC nor an MCC under MS-DRG v44.0.