ICD-10-CM 2027
ICD-10 code for hemolytic newborn disease
From the official ICD-10-CM alphabetic index entry “Disease, diseased › hemolytic (newborn)”. Page updated September 29, 2026.
About coding hemolytic newborn disease
The ICD-10-CM code for hemolytic newborn disease is P55.9 (Hemolytic disease of newborn, unspecified). The official index lists 11 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on P55.9.
Within P55, choose P55.9 (unspecified) only when documentation doesn't support a more specific option: Rh isoimmunization of newborn (P55.0), ABO isoimmunization of newborn (P55.1) and other hemolytic diseases of newborn (P55.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific hemolytic newborn disease codes (official index)
- autoimmune D59.10 — Autoimmune hemolytic anemia, unspecified
- cold type (primary) (secondary) (symptomatic) D59.12 — Cold autoimmune hemolytic anemia
- mixed type (primary) (secondary) (symptomatic) D59.13 — Mixed type autoimmune hemolytic anemia
- warm type (primary) (secondary) (symptomatic) D59.11 — Warm autoimmune hemolytic anemia
- drug-induced D59.0 — Drug-induced autoimmune hemolytic anemia
- due to or with
- incompatibility
- ABO (blood group) P55.1 — ABO isoimmunization of newborn
- blood (group) (Duffy) (K) (Kell) (Kidd) (Lewis) (M) (S) NEC P55.8 — Other hemolytic diseases of newborn
- Rh (blood group) (factor) P55.0 — Rh isoimmunization of newborn
- Rh negative mother P55.0 — Rh isoimmunization of newborn
- specified type NEC P55.8 — Other hemolytic diseases of newborn
- unstable hemoglobin D58.2 — Other hemoglobinopathies
Common questions about hemolytic newborn disease ICD-10 codes
What is the ICD-10 code for hemolytic newborn disease?
- P55.9 — Hemolytic disease of newborn, unspecified. More specific codes apply when the documentation supports them: D59.10, D59.12, D59.13, D59.11 and others below.
What is the ICD-10 code for autoimmune hemolytic newborn disease?
- D59.10 — Autoimmune hemolytic anemia, unspecified.
What is the ICD-10 code for drug-induced hemolytic newborn disease?
- D59.0 — Drug-induced autoimmune hemolytic anemia.
What is the ICD-10 code for unstable hemoglobin hemolytic newborn disease?
- D58.2 — Other hemoglobinopathies.
Is P55.9 billable?
- Yes. P55.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P55.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P55.9 as a principal diagnosis.
Is P55.9 a CC or MCC?
- No. P55.9 is neither a CC nor an MCC under MS-DRG v44.0.