ICD-10-CM 2027
ICD-10 code for HeFH
From the official ICD-10-CM alphabetic index entry “HeFH (heterozygous familial hypercholesterolemia)”. Page updated September 29, 2026.
About coding HeFH
The ICD-10-CM code for HeFH is E78.011 (Heterozygous familial hypercholesterolemia [HeFH]).
Within E78.01 (familial hypercholesterolemia), E78.011 is specifically for Heterozygous familial hypercholesterolemia [HeFH]. Related codes cover Homozygous familial hypercholesterolemia [HoFH] (E78.010) and unspecified (E78.019).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about HeFH ICD-10 codes
What is the ICD-10 code for HeFH?
- E78.011 — Heterozygous familial hypercholesterolemia [HeFH].
Is E78.011 billable?
- Yes. E78.011 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E78.011 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E78.011 as a principal diagnosis.
Is E78.011 a CC or MCC?
- No. E78.011 is neither a CC nor an MCC under MS-DRG v44.0.