ICD-10-CM 2027
ICD-10 code for genital response male failure
From the official ICD-10-CM alphabetic index entry “Failure, failed › genital response (male)”. Page updated September 29, 2026.
About coding genital response male failure
The ICD-10-CM code for genital response male failure is F52.21 (Male erectile disorder). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on F52.21.
Within F52.2 (sexual arousal disorders), F52.21 is specifically for male erectile disorder. Related codes cover female sexual arousal disorder (F52.22).
Don't report F52.21 together with the conditions in its Excludes1 note: impotence of organic origin (N52.-) and impotence NOS (N52.-).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific genital response male failure codes (official index)
- female F52.22 — Female sexual arousal disorder
Don't confuse with (Excludes1 for F52.21)
Common questions about genital response male failure ICD-10 codes
What is the ICD-10 code for genital response male failure?
- F52.21 — Male erectile disorder. More specific codes apply when the documentation supports them: F52.22.
What is the ICD-10 code for female genital response male failure?
- F52.22 — Female sexual arousal disorder.
Is F52.21 billable?
- Yes. F52.21 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F52.21 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F52.21 as a principal diagnosis.
Is F52.21 a CC or MCC?
- No. F52.21 is neither a CC nor an MCC under MS-DRG v44.0.