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ICD-10-CM 2027

ICD-10 code for generalized lipodystrophy

E88.12

Generalized lipodystrophy

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Lipodystrophy › generalized (acquired) (congenital)”. Page updated September 29, 2026.

About coding generalized lipodystrophy

The ICD-10-CM code for generalized lipodystrophy is E88.12 (Generalized lipodystrophy).

Within E88.1 (lipodystrophy, not elsewhere classified), E88.12 is specifically for generalized lipodystrophy. Related codes cover lipodystrophy, unspecified (E88.10), partial lipodystrophy (E88.11), localized lipodystrophy (E88.13), HIV-associated lipodystrophy (E88.14) and other lipodystrophy, not elsewhere classified (E88.19).

Use an additional code for: codes for associated conditions.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

Common questions about generalized lipodystrophy ICD-10 codes

What is the ICD-10 code for generalized lipodystrophy?

E88.12 — Generalized lipodystrophy.

Is E88.12 billable?

Yes. E88.12 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E88.12 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E88.12 as a principal diagnosis.

Is E88.12 a CC or MCC?

No. E88.12 is neither a CC nor an MCC under MS-DRG v44.0.