ICD-10-CM 2027
ICD-10 code for fatigue
Confirmed by the official ICD-10-CM index entry “fatigue”. Page updated September 29, 2026.
About coding fatigue
The ICD-10-CM code for fatigue is R53.83 (Other fatigue). The official index lists 5 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R53.83.
It is also searched as tiredness, malaise.
Within R53.8, choose R53.83 (Other fatigue) only when documentation doesn't support a more specific option: other malaise (R53.81) and chronic fatigue, unspecified (R53.82).
The conditions in its Excludes2 note aren't part of R53.83, but may be coded alongside it if the patient has both: exhaustion and fatigue due to depressive episode (F32.-).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Related Fatigue codes
Common questions about fatigue ICD-10 codes
What is the ICD-10 code for fatigue?
- R53.83 — Other fatigue. More specific codes apply when the documentation supports them: R53.0, R53.1, R53.2, R53.81 and others below.
What is the ICD-10 code for neoplastic (malignant) related fatigue?
- R53.0 — Neoplastic (malignant) related fatigue.
What is the ICD-10 code for weakness?
- R53.1 — Weakness.
What is the ICD-10 code for functional quadriplegia?
- R53.2 — Functional quadriplegia.
What is the ICD-10 code for other malaise?
- R53.81 — Other malaise.
What is the ICD-10 code for chronic fatigue, unspecified?
- R53.82 — Chronic fatigue, unspecified.
Is R53.83 billable?
- Yes. R53.83 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R53.83 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R53.83 as a principal diagnosis.
Is R53.83 a CC or MCC?
- No. R53.83 is neither a CC nor an MCC under MS-DRG v44.0.