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ICD-10-CM 2027

ICD-10 code for Enterococcus sepsis

A41.81

Sepsis due to Enterococcus

From the official ICD-10-CM alphabetic index entry “Sepsis (generalized) (unspecified organism) › Enterococcus”. Page updated September 29, 2026.

About coding Enterococcus sepsis

The ICD-10-CM code for Enterococcus sepsis is A41.81 (Sepsis due to Enterococcus).

Within A41.8 (other specified sepsis), A41.81 is specifically for sepsis due to Enterococcus. Related codes cover other specified sepsis (A41.89).

Code first: , if applicable, postprocedural sepsis (T81.44-), sepsis due to central venous catheter (T80.211-), sepsis during labor (O75.3), sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82) and 2 more.

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

Common questions about Enterococcus sepsis ICD-10 codes

What is the ICD-10 code for Enterococcus sepsis?

A41.81 — Sepsis due to Enterococcus.

Is A41.81 billable?

Yes. A41.81 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can A41.81 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict A41.81 as a principal diagnosis.

Is A41.81 a CC or MCC?

A41.81 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.