ICD-10-CM 2027
ICD-10 code for Endocrinopathy
From the official ICD-10-CM alphabetic index entry “Endocrinopathy, pluriglandular”. Page updated September 29, 2026.
About coding Endocrinopathy
The ICD-10-CM code for Endocrinopathy is E31.9 (Polyglandular dysfunction, unspecified).
Within E31, choose E31.9 (unspecified) only when documentation doesn't support a more specific option: autoimmune polyglandular failure (E31.0), polyglandular hyperfunction (E31.1), multiple endocrine neoplasia [MEN] syndromes (E31.2) and other polyglandular dysfunction (E31.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Endocrinopathy ICD-10 codes
What is the ICD-10 code for Endocrinopathy?
- E31.9 — Polyglandular dysfunction, unspecified.
Is E31.9 billable?
- Yes. E31.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E31.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E31.9 as a principal diagnosis.
Is E31.9 a CC or MCC?
- No. E31.9 is neither a CC nor an MCC under MS-DRG v44.0.