ICD-10-CM 2027
ICD-10 code for DRESS syndrome
From the official ICD-10-CM alphabetic index entry “Syndrome › DRESS (drug rash with eosinophilia and systemic symptoms)”. Page updated September 29, 2026.
About coding DRESS syndrome
The ICD-10-CM code for DRESS syndrome is D72.12 (Drug rash with eosinophilia and systemic symptoms syndrome).
Within D72.1 (eosinophilia), D72.12 is specifically for drug rash with eosinophilia and systemic symptoms syndrome. Related codes cover unspecified (D72.10), hypereosinophilic syndrome [HES] (D72.11), in diseases classified elsewhere (D72.18) and other eosinophilia (D72.19).
Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about DRESS syndrome ICD-10 codes
What is the ICD-10 code for DRESS syndrome?
- D72.12 — Drug rash with eosinophilia and systemic symptoms syndrome.
Is D72.12 billable?
- Yes. D72.12 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D72.12 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D72.12 as a principal diagnosis.
Is D72.12 a CC or MCC?
- No. D72.12 is neither a CC nor an MCC under MS-DRG v44.0.