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ICD-10-CM 2027

ICD-10 code for disease or syndrome addison's

E27.1

Primary adrenocortical insufficiency

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Addison's › disease (bronze) or syndrome”. Page updated September 29, 2026.

About coding disease or syndrome addison's

The ICD-10-CM code for disease or syndrome addison's is E27.1 (Primary adrenocortical insufficiency). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on E27.1.

Within E27 (other disorders of adrenal gland), E27.1 is specifically for primary adrenocortical insufficiency. Related codes cover other adrenocortical overactivity (E27.0), Addisonian crisis (E27.2), drug-induced adrenocortical insufficiency (E27.3), other and unspecified adrenocortical insufficiency (E27.4), Adrenomedullary hyperfunction (E27.5), other specified disorders of adrenal gland (E27.8) and disorder of adrenal gland, unspecified (E27.9).

Don't report E27.1 together with the conditions in its Excludes1 note: Addison only phenotype adrenoleukodystrophy (E71.528), amyloidosis (E85.-), tuberculous Addison's disease (A18.7) and Waterhouse-Friderichsen syndrome (A39.1).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

More specific disease or syndrome addison's codes (official index)

  • tuberculous A18.7 — Tuberculosis of adrenal glands

Don't confuse with (Excludes1 for E27.1)

  • Addison only phenotype adrenoleukodystrophy (E71.528)
  • amyloidosis (E85.-)
  • tuberculous Addison's disease (A18.7)
  • Waterhouse-Friderichsen syndrome (A39.1)

Common questions about disease or syndrome addison's ICD-10 codes

What is the ICD-10 code for disease or syndrome addison's?

E27.1 — Primary adrenocortical insufficiency. More specific codes apply when the documentation supports them: A18.7.

What is the ICD-10 code for tuberculous disease or syndrome addison's?

A18.7 — Tuberculosis of adrenal glands.

Is E27.1 billable?

Yes. E27.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E27.1 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E27.1 as a principal diagnosis.

Is E27.1 a CC or MCC?

E27.1 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.