ICD-10-CM 2027
ICD-10 code for Cushing's syndrome
From the official ICD-10-CM alphabetic index entry “Syndrome › Cushing's”. Page updated September 29, 2026.
About coding Cushing's syndrome
The ICD-10-CM code for Cushing's syndrome is E24.9 (Cushing's syndrome, unspecified). The official index lists 7 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E24.9.
Within E24, choose E24.9 (unspecified) only when documentation doesn't support a more specific option: Pituitary-dependent Cushing's disease (E24.0), Nelson's syndrome (E24.1), drug-induced Cushing's syndrome (E24.2), ectopic ACTH syndrome (E24.3), alcohol-induced pseudo-Cushing's syndrome (E24.4) and other Cushing's syndrome (E24.8).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Cushing's syndrome codes (official index)
- alcohol-induced E24.4 — Alcohol-induced pseudo-Cushing's syndrome
- due to
- alcohol
- drugs E24.2 — Drug-induced Cushing's syndrome
- ectopic ACTH E24.3 — Ectopic ACTH syndrome
- overproduction of pituitary ACTH E24.0 — Pituitary-dependent Cushing's disease
- drug-induced E24.2 — Drug-induced Cushing's syndrome
- overdose or wrong substance given or taken
- pituitary-dependent E24.0 — Pituitary-dependent Cushing's disease
- specified type NEC E24.8 — Other Cushing's syndrome
Common questions about Cushing's syndrome ICD-10 codes
What is the ICD-10 code for Cushing's syndrome?
- E24.9 — Cushing's syndrome, unspecified. More specific codes apply when the documentation supports them: E24.4, E24.2, E24.3, E24.0 and others below.
What is the ICD-10 code for alcohol-induced cushing's syndrome?
- E24.4 — Alcohol-induced pseudo-Cushing's syndrome.
What is the ICD-10 code for drug-induced cushing's syndrome?
- E24.2 — Drug-induced Cushing's syndrome.
What is the ICD-10 code for pituitary-dependent cushing's syndrome?
- E24.0 — Pituitary-dependent Cushing's disease.
Is E24.9 billable?
- Yes. E24.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E24.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E24.9 as a principal diagnosis.
Is E24.9 a CC or MCC?
- E24.9 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.