ICD-10-CM 2027
ICD-10 code for colon endometriosis
From the official ICD-10-CM alphabetic index entry “Endometriosis › colon”. Page updated September 29, 2026.
About coding colon endometriosis
The ICD-10-CM code for colon endometriosis is N80.559 (Endometriosis of other parts of the colon, unspecified depth). The official index lists 9 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on N80.559.
Within N80.55, choose N80.559 (unspecified depth) only when documentation doesn't support a more specific option: superficial endometriosis of other parts of the colon (N80.551) and deep endometriosis of other parts of the colon (N80.552).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC, relative weight 1.2392) and DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC, relative weight 0.7645), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific colon endometriosis codes (official index)
- descending N80.559 — Endometriosis of other parts of the colon, unspecified depth
- deep N80.552 — Deep endometriosis of other parts of the colon
- superficial N80.551 — Superficial endometriosis of other parts of the colon
- sigmoid N80.529 — Endometriosis of the sigmoid colon, unspecified depth
- deep N80.522 — Deep endometriosis of the sigmoid colon
- superficial N80.521 — Superficial endometriosis of the sigmoid colon
- transverse N80.559 — Endometriosis of other parts of the colon, unspecified depth
- deep N80.552 — Deep endometriosis of other parts of the colon
- superficial N80.551 — Superficial endometriosis of other parts of the colon
Common questions about colon endometriosis ICD-10 codes
What is the ICD-10 code for colon endometriosis?
- N80.559 — Endometriosis of other parts of the colon, unspecified depth. More specific codes apply when the documentation supports them: N80.559, N80.552, N80.551, N80.529 and others below.
What is the ICD-10 code for descending colon endometriosis?
- N80.559 — Endometriosis of other parts of the colon, unspecified depth.
What is the ICD-10 code for sigmoid colon endometriosis?
- N80.529 — Endometriosis of the sigmoid colon, unspecified depth.
What is the ICD-10 code for transverse colon endometriosis?
- N80.559 — Endometriosis of other parts of the colon, unspecified depth.
Is N80.559 billable?
- Yes. N80.559 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can N80.559 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict N80.559 as a principal diagnosis.
Is N80.559 a CC or MCC?
- No. N80.559 is neither a CC nor an MCC under MS-DRG v44.0.