ICD-10-CM 2027
ICD-10 code for cold hemoglobinuria
From the official ICD-10-CM alphabetic index entry “Hemoglobinuria › cold (paroxysmal) (with Raynaud's syndrome)”. Page updated September 29, 2026.
About coding cold hemoglobinuria
The ICD-10-CM code for cold hemoglobinuria is D59.6 (Hemoglobinuria due to hemolysis from other external causes). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on D59.6.
Within D59, choose D59.6 (Hemoglobinuria due to hemolysis from other external causes) only when documentation doesn't support a more specific option: drug-induced autoimmune hemolytic anemia (D59.0), other autoimmune hemolytic anemias (D59.1), drug-induced nonautoimmune hemolytic anemia (D59.2), hemolytic-uremic syndrome (D59.3), other nonautoimmune hemolytic anemias (D59.4), paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] (D59.5), other acquired hemolytic anemias (D59.8) and unspecified (D59.9).
Don't report D59.6 together with the conditions in its Excludes1 note: hemoglobinuria NOS (R82.3).
Use an additional code (Chapter 20) to identify external cause.
More specific cold hemoglobinuria codes (official index)
- agglutinin D59.12 — Cold autoimmune hemolytic anemia
Don't confuse with (Excludes1 for D59.6)
- hemoglobinuria NOS (R82.3)
Common questions about cold hemoglobinuria ICD-10 codes
What is the ICD-10 code for cold hemoglobinuria?
- D59.6 — Hemoglobinuria due to hemolysis from other external causes. More specific codes apply when the documentation supports them: D59.12.
What is the ICD-10 code for agglutinin cold hemoglobinuria?
- D59.12 — Cold autoimmune hemolytic anemia.
Is D59.6 billable?
- Yes. D59.6 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D59.6 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D59.6 as a principal diagnosis.
Is D59.6 a CC or MCC?
- No. D59.6 is neither a CC nor an MCC under MS-DRG v44.0.