ICD-10-CM 2027
ICD-10 code for chromosome mosaics sex
From the official ICD-10-CM alphabetic index entry “Sex › chromosome mosaics”. Page updated September 29, 2026.
About coding chromosome mosaics sex
The ICD-10-CM code for chromosome mosaics sex is Q97.8 (Other specified sex chromosome abnormalities, female phenotype). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on Q97.8.
Within Q97, choose Q97.8 (Other specified sex chromosome abnormalities, female phenotype) only when documentation doesn't support a more specific option: karyotype 47, XXX (Q97.0), female with more than three X chromosomes (Q97.1), mosaicism, lines with various numbers of X chromosomes (Q97.2), female with 46, XY karyotype (Q97.3) and sex chromosome abnormality, female phenotype, unspecified (Q97.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 742 (Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC, relative weight 1.8456), DRG 743 (Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC, relative weight 1.2974), DRG 760 (Menstrual and Other Female Reproductive System Disorders with CC/MCC, relative weight 1.0129) and DRG 761 (Menstrual and Other Female Reproductive System Disorders without CC/MCC, relative weight 0.7041), in MDC 13 (Diseases and Disorders of the Female Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific chromosome mosaics sex codes (official index)
- lines with various numbers of X chromosomes Q97.2 — Mosaicism, lines with various numbers of X chromosomes
Common questions about chromosome mosaics sex ICD-10 codes
What is the ICD-10 code for chromosome mosaics sex?
- Q97.8 — Other specified sex chromosome abnormalities, female phenotype. More specific codes apply when the documentation supports them: Q97.2.
Is Q97.8 billable?
- Yes. Q97.8 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Q97.8 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict Q97.8 as a principal diagnosis.
Is Q97.8 a CC or MCC?
- No. Q97.8 is neither a CC nor an MCC under MS-DRG v44.0.