ICD-10 code for central nervous system demyelination

The ICD-10-CM code for central nervous system demyelination is G37.9 (Demyelinating disease of central nervous system, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on G37.9.

Within G37, choose G37.9 (Demyelinating disease of central nervous system, unspecified) only when documentation doesn't support a more specific option: diffuse sclerosis of central nervous system (G37.0), central demyelination of corpus callosum (G37.1), central pontine myelinolysis (G37.2), acute transverse myelitis in demyelinating disease of central nervous system (G37.3), subacute necrotizing myelitis of central nervous system (G37.4), Concentric sclerosis [Balo] of central nervous system (G37.5) and other specified demyelinating diseases of central nervous system (G37.8).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 058 (Multiple Sclerosis and Cerebellar Ataxia with MCC, relative weight 1.8438), DRG 059 (Multiple Sclerosis and Cerebellar Ataxia with CC, relative weight 1.2002), DRG 060 (Multiple Sclerosis and Cerebellar Ataxia without CC/MCC, relative weight 0.9247), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506), DRG 975 (HIV with Major Related Condition with CC, relative weight 1.3252) and DRG 976 (HIV with Major Related Condition without CC/MCC, relative weight 0.8124), in MDC 01 (Diseases and Disorders of the Nervous System) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.